GTF2E2
General transcription factor IIE subunit 2 (GTF2E2), also known as transcription initiation factor IIE subunit beta (TFIIE-beta), is a protein that in humans is encoded by the GTF2E2 gene.[1]
See also
References
Further reading
- Jeronimo C, Forget D, Bouchard A, et al. (2007). "Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme". Mol. Cell 27 (2): 262–74. doi:10.1016/j.molcel.2007.06.027. PMID 17643375.
- Tanaka A, Watanabe T, Iida Y, et al. (2009). "Central forkhead domain of human TFIIE beta plays a primary role in binding double-stranded DNA at transcription initiation". Genes Cells 14 (3): 395–405. doi:10.1111/j.1365-2443.2008.01278.x. PMID 19210545.
- Kang SW, Kuzuhara T, Horikoshi M (2000). "Functional interaction of general transcription initiation factor TFIIE with general chromatin factor SPT16/CDC68". Genes Cells 5 (4): 251–63. doi:10.1046/j.1365-2443.2000.00323.x. PMID 10792464.
- Langelier MF, Forget D, Rojas A, et al. (2001). "Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II". J. Biol. Chem. 276 (42): 38652–7. doi:10.1074/jbc.M106422200. PMID 11509574.
- Yamamoto S, Watanabe Y, van der Spek PJ, et al. (2001). "Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation". Mol. Cell. Biol. 21 (1): 1–15. doi:10.1128/MCB.21.1.1-15.2001. PMC 86563. PMID 11113176.
- Watanabe T, Hayashi K, Tanaka A, et al. (2003). "The carboxy terminus of the small subunit of TFIIE regulates the transition from transcription initiation to elongation by RNA polymerase II". Mol. Cell. Biol. 23 (8): 2914–26. doi:10.1128/mcb.23.8.2914-2926.2003. PMC 152561. PMID 12665589.
- Jawhari A, Uhring M, De Carlo S, et al. (2006). "Structure and oligomeric state of human transcription factor TFIIE". EMBO Rep. 7 (5): 500–5. doi:10.1038/sj.embor.7400663. PMC 1479554. PMID 16547462.
- Orphanides G, Lagrange T, Reinberg D (1996). "The general transcription factors of RNA polymerase II". Genes Dev. 10 (21): 2657–83. doi:10.1101/gad.10.21.2657. PMID 8946909.
- Kim TK, Ebright RH, Reinberg D (2000). "Mechanism of ATP-dependent promoter melting by transcription factor IIH". Science 288 (5470): 1418–22. doi:10.1126/science.288.5470.1418. PMID 10827951.
- Ikeda K, Halle JP, Stelzer G, et al. (1998). "Involvement of negative cofactor NC2 in active repression by zinc finger-homeodomain transcription factor AREB6". Mol. Cell. Biol. 18 (1): 10–8. PMC 121442. PMID 9418848.
- Holstege FC, Fiedler U, Timmers HT (1997). "Three transitions in the RNA polymerase II transcription complex during initiation". EMBO J. 16 (24): 7468–80. doi:10.1093/emboj/16.24.7468. PMC 1170346. PMID 9405375.
- Cirulli ET, Kasperavičiūtė D, Attix DK, et al. (2010). "Common genetic variation and performance on standardized cognitive tests". Eur. J. Hum. Genet. 18 (7): 815–20. doi:10.1038/ejhg.2010.2. PMC 2987367. PMID 20125193.
- Yu X, Li P, Roeder RG, Wang Z (2001). "Inhibition of androgen receptor-mediated transcription by amino-terminal enhancer of split". Mol. Cell. Biol. 21 (14): 4614–25. doi:10.1128/MCB.21.14.4614-4625.2001. PMC 87125. PMID 11416139.
- Yokomori K, Verrijzer CP, Tjian R (1998). "An interplay between TATA box-binding protein and transcription factors IIE and IIA modulates DNA binding and transcription". Proc. Natl. Acad. Sci. U.S.A. 95 (12): 6722–7. doi:10.1073/pnas.95.12.6722. PMC 22611. PMID 9618479.
- Liu L, Ishihara K, Ichimura T, et al. (2009). "MCAF1/AM is involved in Sp1-mediated maintenance of cancer-associated telomerase activity". J. Biol. Chem. 284 (8): 5165–74. doi:10.1074/jbc.M807098200. PMID 19106100.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- De Graeve F, Bahr A, Chatton B, Kedinger C (2000). "A murine ATFa-associated factor with transcriptional repressing activity". Oncogene 19 (14): 1807–19. doi:10.1038/sj.onc.1203492. PMID 10777215.
- Okamoto T, Yamamoto S, Watanabe Y, et al. (1998). "Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit". J. Biol. Chem. 273 (31): 19866–76. doi:10.1074/jbc.273.31.19866. PMID 9677423.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Festen EA, Stokkers PC, van Diemen CC, et al. (2010). "Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk". Am. J. Gastroenterol. 105 (2): 395–402. doi:10.1038/ajg.2009.576. PMID 19861958.
PDB gallery |
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| | 1d8k: SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA |
| 1d8j: SOLUTION STRUCTURE OF THE CENTRAL CORE DOMAIN OF TFIIE BETA |
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| (2.1) Nuclear receptor (Cys4) | subfamily 1 | |
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| subfamily 2 | |
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| subfamily 3 | |
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| subfamily 4 | |
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| subfamily 5 | |
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| subfamily 6 | |
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| subfamily 0 | |
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| (2.2) Other Cys4 | |
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| (2.3) Cys2His2 | |
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| (2.4) Cys6 | |
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| (2.5) Alternating composition | |
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| (2.6) WRKY | |
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| | | | (4) β-Scaffold factors with minor groove contacts |
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| | (0) Other transcription factors |
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| | see also transcription factor/coregulator deficiencies |
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