GTF3A
| General transcription factor IIIA | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||
| Symbols | GTF3A ; AP2; TFIIIA | ||||||||||||
| External IDs | OMIM: 600860 HomoloGene: 55630 GeneCards: GTF3A Gene | ||||||||||||
| |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 2971 | 66596 | |||||||||||
| Ensembl | ENSG00000122034 | ENSMUSG00000016503 | |||||||||||
| UniProt | Q92664 | Q8VHT7 | |||||||||||
| RefSeq (mRNA) | NM_002097 | NM_025652 | |||||||||||
| RefSeq (protein) | NP_002088 | NP_079928 | |||||||||||
| Location (UCSC) |
Chr 13: 27.42 – 27.44 Mb |
Chr 5: 146.95 – 146.96 Mb | |||||||||||
| PubMed search | |||||||||||||
Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.[1][2]
References
- ↑ Arakawa H, Nagase H, Hayashi N, Ogawa M, Nagata M, Fujiwara T, Takahashi E, Shin S, Nakamura Y (Jul 1995). "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenetics and Cell Genetics 70 (3-4): 235–8. doi:10.1159/000134041. PMID 7789179.
- ↑ "Entrez Gene: GTF3A general transcription factor IIIA".
Further reading
- Murphy JE, Keen JH (May 1992). "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia". The Journal of Biological Chemistry 267 (15): 10850–5. PMID 1587861.
- Seifart KH, Wang L, Waldschmidt R, Jahn D, Wingender E (Jan 1989). "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA". The Journal of Biological Chemistry 264 (3): 1702–9. PMID 2912980.
- Drew PD, Nagle JW, Canning RD, Ozato K, Biddison WE, Becker KG (Jul 1995). "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene 159 (2): 215–8. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.
- Moorefield B, Roeder RG (Aug 1994). "Purification and characterization of human transcription factor IIIA". The Journal of Biological Chemistry 269 (33): 20857–65. PMID 8063702.
- Fridell RA, Fischer U, Lührmann R, Meyer BE, Meinkoth JL, Malim MH, Cullen BR (Apr 1996). "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proceedings of the National Academy of Sciences of the United States of America 93 (7): 2936–40. doi:10.1073/pnas.93.7.2936. PMC 39738. PMID 8610146.
- Oettel S, Härtel F, Kober I, Iben S, Seifart KH (Jun 1997). "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Research 25 (12): 2440–7. doi:10.1093/nar/25.12.2440. PMC 146769. PMID 9171097.
- Moreland RJ, Dresser ME, Rodgers JS, Roe BA, Conaway JW, Conaway RC, Hanas JS (May 2000). "Identification of a transcription factor IIIA-interacting protein". Nucleic Acids Research 28 (9): 1986–93. doi:10.1093/nar/28.9.1986. PMC 103300. PMID 10756201.
- Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS (Nov 2001). "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors". Molecular and Cellular Biology 21 (22): 7796–806. doi:10.1128/MCB.21.22.7796-7806.2001. PMC 99949. PMID 11604514.
- Hanas JS, Hocker JR, Cheng YG, Lerner MR, Brackett DJ, Lightfoot SA, Hanas RJ, Madhusudhan KT, Moreland RJ (Jan 2002). "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene 282 (1-2): 43–52. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.
- Weser S, Riemann J, Seifart KH, Meissner W (May 2003). "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene". Nucleic Acids Research 31 (9): 2408–16. doi:10.1093/nar/gkg345. PMC 154231. PMID 12711686.
- Pellikainen JM, Ropponen KM, Kataja VV, Kellokoski JK, Eskelinen MJ, Kosma VM (Nov 2004). "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clinical Cancer Research 10 (22): 7621–8. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
- Paing MM, Johnston CA, Siderovski DP, Trejo J (Apr 2006). "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization". Molecular and Cellular Biology 26 (8): 3231–42. doi:10.1128/MCB.26.8.3231-3242.2006. PMC 1446942. PMID 16581796.
- Yamashita A, Takada T, Nemoto K, Yamamoto G, Torii R (Jul 2006). "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Letters 580 (17): 4121–5. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.
- Schwartz B, Melnikova VO, Tellez C, Mourad-Zeidan A, Blehm K, Zhao YJ, McCarty M, Adam L, Bar-Eli M (Jun 2007). "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo". Oncogene 26 (28): 4049–58. doi:10.1038/sj.onc.1210193. PMID 17224907.
- Hannay JA, Liu J, Zhu QS, Bolshakov SV, Li L, Pisters PW, Lazar AJ, Yu D, Pollock RE, Lev D (May 2007). "Rad51 overexpression contributes to chemoresistance in human soft tissue sarcoma cells: a role for p53/activator protein 2 transcriptional regulation". Molecular Cancer Therapeutics 6 (5): 1650–60. doi:10.1158/1535-7163.MCT-06-0636. PMID 17513613.
External links
- GTF3A protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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